Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50006274
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at HCA2 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at HCA2 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 3(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50208138((+)-acifran | 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-...)
Affinity DataEC50:  316nMAssay Description:Agonist activity at HCA3 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498352(CHEMBL3589834)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM23520(2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanami...)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498355(CHEMBL3589835)
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50342530(2-(3-(4'-hydroxybiphenyl-4-yl)propanamido)benzoic ...)
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498357(CHEMBL3589788)
Affinity DataIC50: 83nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498351(CHEMBL3589790)
Affinity DataIC50: 86nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498349(CHEMBL3589793)
Affinity DataIC50: 91nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50319257(2-(3-(2'-chlorobiphenyl-4-yl)propanamido)benzoicac...)
Affinity DataIC50: 94nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498360(CHEMBL3589837)
Affinity DataIC50: 105nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50268988(CHEMBL3589836)
Affinity DataIC50: 108nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498350(CHEMBL3589833)
Affinity DataIC50: 129nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498348(CHEMBL3589791)
Affinity DataIC50: 201nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 249nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498346(CHEMBL3589785)
Affinity DataIC50: 283nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM23519(2-[3-(4-phenylphenyl)propanamido]benzoic acid | CH...)
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498344(CHEMBL3589779)
Affinity DataIC50: 323nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498356(CHEMBL3589789)
Affinity DataIC50: 326nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498354(CHEMBL3589792)
Affinity DataIC50: 365nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498353(CHEMBL3589787)
Affinity DataIC50: 555nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498358(CHEMBL3589783)
Affinity DataIC50: 769nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498359(CHEMBL3589782)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498347(CHEMBL3589786)
Affinity DataIC50: 940nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50498345(CHEMBL3589784)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed