Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50045728
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078642(CHEMBL3415384)
Affinity DataKd:  0.136nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078643(CHEMBL3415383)
Affinity DataKd:  0.0900nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKd:  0.0890nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078644(CHEMBL3415382)
Affinity DataKd:  0.170nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078670(CHEMBL3415381)
Affinity DataKd:  0.800nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078671(CHEMBL3415380)
Affinity DataKd:  0.0340nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078672(CHEMBL3415379)
Affinity DataKd:  0.0830nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKd:  0.0430nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078643(CHEMBL3415383)
Affinity DataIC50: 31nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078672(CHEMBL3415379)
Affinity DataIC50: 31nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078671(CHEMBL3415380)
Affinity DataIC50: 47nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078644(CHEMBL3415382)
Affinity DataIC50: 82nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078670(CHEMBL3415381)
Affinity DataIC50: 156nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078642(CHEMBL3415384)
Affinity DataIC50: 165nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed