Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50045486
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064471(CHEMBL3401173)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064457(CHEMBL3401182)
Affinity DataEC50:  3.58E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064458(CHEMBL3401181)
Affinity DataEC50:  2.00E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064459(CHEMBL3401180)
Affinity DataEC50:  587nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064460(CHEMBL3401179)
Affinity DataEC50:  230nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064461(CHEMBL3401178)
Affinity DataEC50:  514nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064468(CHEMBL3401176)
Affinity DataEC50:  1.59E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064469(CHEMBL3401175)
Affinity DataEC50:  1.12E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064470(CHEMBL3401174)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064456(CHEMBL3401183)
Affinity DataEC50:  5.10E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064444(CHEMBL3401195)
Affinity DataEC50:  86nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064430(CHEMBL3401203)
Affinity DataEC50:  285nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064431(CHEMBL3401202)
Affinity DataEC50:  197nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064432(CHEMBL3400160)
Affinity DataEC50:  69nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064433(CHEMBL3401201)
Affinity DataEC50:  371nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064434(CHEMBL3401200)
Affinity DataEC50:  183nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064435(CHEMBL3401199)
Affinity DataEC50:  485nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064436(CHEMBL3401198)
Affinity DataEC50:  359nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064442(CHEMBL3401197)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064443(CHEMBL3401196)
Affinity DataEC50:  218nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064431(CHEMBL3401202)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064445(CHEMBL3401193)
Affinity DataEC50:  2.07E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064446(CHEMBL3401191)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064447(CHEMBL3401190)
Affinity DataEC50:  3.17E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064448(CHEMBL3401189)
Affinity DataEC50:  344nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064449(CHEMBL3401188)
Affinity DataEC50:  375nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064450(CHEMBL3401187)
Affinity DataEC50:  230nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064452(CHEMBL3401186)
Affinity DataEC50:  435nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064453(CHEMBL3401185)
Affinity DataEC50:  375nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064454(CHEMBL3401184)
Affinity DataEC50:  284nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064445(CHEMBL3401193)
Affinity DataEC50:  2.09E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064456(CHEMBL3401183)
Affinity DataEC50:  5.13E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064454(CHEMBL3401184)
Affinity DataEC50:  282nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064453(CHEMBL3401185)
Affinity DataEC50:  372nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064452(CHEMBL3401186)
Affinity DataEC50:  437nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064450(CHEMBL3401187)
Affinity DataEC50:  229nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064449(CHEMBL3401188)
Affinity DataEC50:  372nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064448(CHEMBL3401189)
Affinity DataEC50:  347nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064447(CHEMBL3401190)
Affinity DataEC50:  3.16E+3nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064446(CHEMBL3401191)
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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