Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50045412
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061298(CHEMBL3393837)
Affinity DataIC50: 0.550nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of 45 degC heat-induced effect at 1 uM by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061298(CHEMBL3393837)
Affinity DataKi:  0.0200nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of NADA-induced effect at 1 uM by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061298(CHEMBL3393837)
Affinity DataKi:  0.200nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061352(CHEMBL3393836)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061319(CHEMBL3393838)
Affinity DataKi:  0.700nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061302(CHEMBL3393840)
Affinity DataKi:  1.80nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061359(CHEMBL3393826)
Affinity DataKi:  7.10nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061357(CHEMBL3393828)
Affinity DataKi:  7.20nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061354(CHEMBL3393833)
Affinity DataKi:  7.80nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061358(CHEMBL3393827)
Affinity DataKi:  8.40nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061355(CHEMBL3393832)
Affinity DataKi:  8.90nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061356(CHEMBL3393830)
Affinity DataKi:  9.5nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50147083(1-(4-tert-Butyl-benzyl)-3-isoquinolin-5-yl-urea | ...)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM20334(1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...)
Affinity DataKi:  18nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061301(CHEMBL3393842)
Affinity DataKi:  48nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061353(CHEMBL3393835)
Affinity DataKi:  92nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed