Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50045055
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043704(CHEMBL3356001)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043768(CHEMBL3355999)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043705(CHEMBL3356002)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043771(CHEMBL3355996)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043704(CHEMBL3356001)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043706(CHEMBL3356003)
Affinity DataIC50: 7nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043703(CHEMBL3356000)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043769(CHEMBL3355998)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043768(CHEMBL3355999)
Affinity DataIC50: 11nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043709(CHEMBL3356006)
Affinity DataIC50: 12nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043772(CHEMBL3355995)
Affinity DataIC50: 12nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043766(CHEMBL3356009)
Affinity DataIC50: 13nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043710(CHEMBL3356007)
Affinity DataIC50: 14nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043770(CHEMBL3355997)
Affinity DataIC50: 14nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043776(CHEMBL3355993)
Affinity DataIC50: 14nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043706(CHEMBL3356003)
Affinity DataIC50: 14nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043705(CHEMBL3356002)
Affinity DataIC50: 20nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043726(CHEMBL3356008)
Affinity DataIC50: 22nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043771(CHEMBL3355996)
Affinity DataIC50: 29nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043769(CHEMBL3355998)
Affinity DataIC50: 31nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043767(CHEMBL3356010)
Affinity DataIC50: 31nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043775(CHEMBL3355994)
Affinity DataIC50: 32nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043703(CHEMBL3356000)
Affinity DataIC50: 43nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043707(CHEMBL3356004)
Affinity DataIC50: 45nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043770(CHEMBL3355997)
Affinity DataIC50: 51nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043708(CHEMBL3356005)
Affinity DataIC50: 54nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043777(CHEMBL3355992)
Affinity DataIC50: 71nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043772(CHEMBL3355995)
Affinity DataIC50: 170nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043777(CHEMBL3355992)
Affinity DataIC50: 350nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043767(CHEMBL3356010)
Affinity DataIC50: 400nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043709(CHEMBL3356006)
Affinity DataIC50: 400nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043726(CHEMBL3356008)
Affinity DataIC50: 540nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043776(CHEMBL3355993)
Affinity DataIC50: 710nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043708(CHEMBL3356005)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043710(CHEMBL3356007)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043707(CHEMBL3356004)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043766(CHEMBL3356009)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043775(CHEMBL3355994)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed