Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50035817
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000780(CHEMBL593781 | 2-(3,4-dichlorophenyl)-N-methyl-N-[...)
Affinity DataKi:  0.890nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor kappa 1 using [3H]BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000780(CHEMBL593781 | 2-(3,4-dichlorophenyl)-N-methyl-N-[...)
Affinity DataKi:  44nMAssay Description:Compound was evaluated for binding affinity towards kappa opioid receptor using [3H]-BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  81nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  109nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor kappa 1 using [3H]BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50008848(CHEMBL301867 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  118nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H]DTG in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  167nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor kappa 1 using [3H]BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50008848(CHEMBL301867 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  221nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  250nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H]DTG in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  299nMAssay Description:Compound was evaluated for binding affinity towards kappa opioid receptor using [3H](-)-U-69,593 in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000780(CHEMBL593781 | 2-(3,4-dichlorophenyl)-N-methyl-N-[...)
Affinity DataKi:  594nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  874nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  874nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  1.30E+3nMAssay Description:Compound was evaluated for binding affinity towards kappa opioid receptor using [3H]-BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50008848(CHEMBL301867 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  2.72E+3nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor kappa 1 using [3H]BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  3.73E+3nMAssay Description:Compound was evaluated for binding affinity towards Dopamine receptor D2 using [3H]SULP in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50008848(CHEMBL301867 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  1.40E+4nMAssay Description:Compound was evaluated for binding affinity towards Dopamine receptor D2 using [3H]SULP in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed