Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50044984
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068459(1-[2-(4-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068454(1-[2-(3-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040266(CHEMBL3359513)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040256(CHEMBL3352893)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068450(1-[2-(2-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50338990(CHEMBL2311153 | N-phenylpropyl-N''-3,4-dimethoxyph...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040264(CHEMBL3360017)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040265(CHEMBL3360016)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040258(CHEMBL3360026)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040263(CHEMBL3360019)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040261(CHEMBL3360024)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040251(CHEMBL3360018)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040259(CHEMBL3360025)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040257(CHEMBL3360027)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040255(CHEMBL3360023)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040262(CHEMBL3360021)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040252(CHEMBL3360020)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040254(CHEMBL3360022)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040259(CHEMBL3360025)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040255(CHEMBL3360023)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040252(CHEMBL3360020)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040255(CHEMBL3360023)
Affinity DataKi:  128nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040251(CHEMBL3360018)
Affinity DataKi:  174nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040263(CHEMBL3360019)
Affinity DataKi:  237nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040254(CHEMBL3360022)
Affinity DataKi:  295nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040256(CHEMBL3352893)
Affinity DataKi:  468nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040251(CHEMBL3360018)
Affinity DataKi:  560nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50338990(CHEMBL2311153 | N-phenylpropyl-N''-3,4-dimethoxyph...)
Affinity DataKi:  760nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068454(1-[2-(3-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  985nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068454(1-[2-(3-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068459(1-[2-(4-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  1.47E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068459(1-[2-(4-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Affinity DataKi:  1.73E+3nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040252(CHEMBL3360020)
Affinity DataKi:  1.82E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040256(CHEMBL3352893)
Affinity DataKi:  1.84E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040254(CHEMBL3360022)
Affinity DataKi:  2.08E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  2.87E+3nMAssay Description:Displacement of [3H]paroxetine from mouse SERT in whole brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50068452(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Affinity DataKi:  8.20E+3nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50040266(CHEMBL3359513)
Affinity DataKi:  1.27E+4nMAssay Description:Displacement of [3H]RTI-121 from mouse DAT in striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed