Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50045427
TargetHepatocyte growth factor receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of c-Met kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296896((S)-2-(3-(3-hydroxy-5-methylphenyl)-4-(6-(2-hydrox...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062357(CHEMBL3397300 | AP26113)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296896((S)-2-(3-(3-hydroxy-5-methylphenyl)-4-(6-(2-hydrox...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062357(CHEMBL3397300 | AP26113)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROS1 (unknown origin) expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROS1 (unknown origin) expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-Met kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296896((S)-2-(3-(3-hydroxy-5-methylphenyl)-4-(6-(2-hydrox...)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-Met (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062373(CHEMBL3397291)
Affinity DataIC50: 24nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 24nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062380(CHEMBL3397286)
Affinity DataIC50: 56nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062367(CHEMBL3397288)
Affinity DataIC50: 88nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062365(CHEMBL3397290)
Affinity DataIC50: 108nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062382(CHEMBL3397285)
Affinity DataIC50: 119nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062369(CHEMBL3397287)
Affinity DataIC50: 148nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062370(CHEMBL3397293)
Affinity DataIC50: 183nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 199nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062361(CHEMBL3397299)
Affinity DataIC50: 330nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062359(CHEMBL3397295)
Affinity DataIC50: 357nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062371(CHEMBL3397292)
Affinity DataIC50: 478nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062360(CHEMBL3397298)
Affinity DataIC50: 570nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296896((S)-2-(3-(3-hydroxy-5-methylphenyl)-4-(6-(2-hydrox...)
Affinity DataIC50: 775nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062366(CHEMBL3397289)
Affinity DataIC50: 780nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062384(CHEMBL3397284)
Affinity DataIC50: 920nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062378(CHEMBL3397301)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of ROS1 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062358(CHEMBL3397294)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062380(CHEMBL3397286)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062373(CHEMBL3397291)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062382(CHEMBL3397285)
Affinity DataIC50: 4.32E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062367(CHEMBL3397288)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062377(CHEMBL3397302)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of ROS1 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062365(CHEMBL3397290)
Affinity DataIC50: 9.72E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062369(CHEMBL3397287)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062373(CHEMBL3397291)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062370(CHEMBL3397293)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062371(CHEMBL3397292)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062367(CHEMBL3397288)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062380(CHEMBL3397286)
Affinity DataIC50: 3.39E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062382(CHEMBL3397285)
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062370(CHEMBL3397293)
Affinity DataIC50: 5.55E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062369(CHEMBL3397287)
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062365(CHEMBL3397290)
Affinity DataIC50: 7.34E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062371(CHEMBL3397292)
Affinity DataIC50: 9.09E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed