Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50045386
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50036738((R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50036734((S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]-7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50036734((S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50059789(CHEMBL3393789)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50059787(CHEMBL3393790)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50036738((R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  256nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50036734((S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  353nMAssay Description:Displacement of [3H]-7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50036738((R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  1.28E+3nMAssay Description:Displacement of [3H]-7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50059787(CHEMBL3393790)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50059789(CHEMBL3393789)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50059787(CHEMBL3393790)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50059789(CHEMBL3393789)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed