Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50044910
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035880(CHEMBL1437990)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035856(CHEMBL1345545)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035855(CHEMBL1505015)
Affinity DataIC50: 2.29E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035860(CHEMBL3361009)
Affinity DataIC50: 3.37E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035870(CHEMBL3361017)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035857(CHEMBL1451460)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035879(CHEMBL3361026)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035878(CHEMBL3361025)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035877(CHEMBL3361024)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035876(CHEMBL3361023)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035875(CHEMBL3361022)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035874(CHEMBL3361021)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035873(CHEMBL3361020)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035872(CHEMBL3361019)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035871(CHEMBL3361018)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035858(CHEMBL3361008)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035869(CHEMBL3361016)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035868(GNF-Pf-4873 | SJ000233075 | TCMDC-123816 | CHEMBL5...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035867(CHEMBL3352903)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035866(CHEMBL3361015)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035865(CHEMBL3361014)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035864(CHEMBL3361013)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035863(CHEMBL3361012)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035862(CHEMBL3361011)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035861(CHEMBL3361010)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035859(CHEMBL1597544)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed