Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50046258
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM21130(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102832(CHEMBL3339379)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102833(CHEMBL3339378)
Affinity DataEC50:  0.0330nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  0.720nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102833(CHEMBL3339378)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102832(CHEMBL3339379)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102833(CHEMBL3339378)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102832(CHEMBL3339379)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102826(CHEMBL3339374)
Affinity DataKi:  0.0370nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102833(CHEMBL3339378)
Affinity DataKi:  0.0430nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102826(CHEMBL3339374)
Affinity DataKi:  0.0520nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102828(CHEMBL3339372)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102832(CHEMBL3339379)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102828(CHEMBL3339372)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102833(CHEMBL3339378)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102830(CHEMBL3339381)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102826(CHEMBL3339374)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102830(CHEMBL3339381)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102831(CHEMBL3339380)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102831(CHEMBL3339380)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102835(CHEMBL3339376)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102834(CHEMBL3339377)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102834(CHEMBL3339377)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102834(CHEMBL3339377)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102832(CHEMBL3339379)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102825(CHEMBL3339375)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102830(CHEMBL3339381)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102833(CHEMBL3339378)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102827(CHEMBL3339373)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102831(CHEMBL3339380)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102832(CHEMBL3339379)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102828(CHEMBL3339372)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102835(CHEMBL3339376)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102825(CHEMBL3339375)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102827(CHEMBL3339373)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102825(CHEMBL3339375)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102835(CHEMBL3339376)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50102827(CHEMBL3339373)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50325534(nalfurafine | CHEMBL267495)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed