Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50046257
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102819(CHEMBL3339368)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102824(CHEMBL3339359)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102823(CHEMBL3339356)
Affinity DataIC50: 5nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102820(CHEMBL3339354)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102821(CHEMBL3339353)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: 29nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: 45nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50351728(CHEMBL1822590)
Affinity DataIC50: 54nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: 390nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: 560nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed