Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50044767
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029089(CHEMBL3360821)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029089(CHEMBL3360821)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029089(CHEMBL3360821)
Affinity DataIC50: 600nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029088(CHEMBL3360820)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029088(CHEMBL3360820)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029087(CHEMBL3360819)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029087(CHEMBL3360819)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029087(CHEMBL3360819)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029086(CHEMBL3360816)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029086(CHEMBL3360816)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029086(CHEMBL3360816)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029088(CHEMBL3360820)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed