Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 6815
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM152804((2E)-2-(N-hydroxyimino)-1-(4-methanesulfonylphenyl...)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 600nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM152806((2E)-2-(4-fluorophenyl)-2-(N-hydroxyimino)-1-(4-me...)
Affinity DataIC50: 1.10E+3nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.10E+3nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.85E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM152802((2E)-2-(N-hydroxyimino)-1-(4-methanesulfonylphenyl...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM152803((2E)-2-(N-hydroxyimino)-1-(4-methanesulfonylphenyl...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM152805((2E)-2-(4-chlorophenyl)-2-(N-hydroxyimino)-1-(4-me...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM152802((2E)-2-(N-hydroxyimino)-1-(4-methanesulfonylphenyl...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM152803((2E)-2-(N-hydroxyimino)-1-(4-methanesulfonylphenyl...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM152804((2E)-2-(N-hydroxyimino)-1-(4-methanesulfonylphenyl...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM152805((2E)-2-(4-chlorophenyl)-2-(N-hydroxyimino)-1-(4-me...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Mazandaran University of Medical Sciences

LigandPNGBDBM152806((2E)-2-(4-fluorophenyl)-2-(N-hydroxyimino)-1-(4-me...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Mazandaran University of Medical Sciences

LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.13E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed