Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50044702
TargetHistone deacetylase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026641(CHEMBL3335367)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026642(CHEMBL3335368)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026629(CHEMBL3334509)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed