Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 6461
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  30nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  50nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  153nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  198nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  212nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  265nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  352nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  393nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  632nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial [1-973,L111A](Bovine)
University of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  1.18E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
University of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.19E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  1.93E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial [1-973,Y477A](Bovine)
University of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  3.49E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial [1-973,L111A](Bovine)
University of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  7.27E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.06E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial [1-973,Y477A](Bovine)
University of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.54E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  4.13E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  5.58E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)