Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50045307
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056134(CHEMBL3322160)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056127(CHEMBL3322142)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056124(CHEMBL3322157)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056127(CHEMBL3322142)
Affinity DataIC50: 228nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056125(CHEMBL3322140)
Affinity DataIC50: 233nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataIC50: 267nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056131(CHEMBL3322159)
Affinity DataIC50: 277nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056134(CHEMBL3322160)
Affinity DataIC50: 328nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056129(CHEMBL3322156)
Affinity DataIC50: 398nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056128(CHEMBL3322155)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056125(CHEMBL3322140)
Affinity DataIC50: 765nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056131(CHEMBL3322159)
Affinity DataIC50: 827nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056135(CHEMBL3322161)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056128(CHEMBL3322155)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056124(CHEMBL3322157)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056129(CHEMBL3322156)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056130(CHEMBL3322158)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056135(CHEMBL3322161)
Affinity DataIC50: 8.17E+3nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056130(CHEMBL3322158)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056134(CHEMBL3322160)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056134(CHEMBL3322160)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataKi:  79nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataKi:  80nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKi:  101nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056127(CHEMBL3322142)
Affinity DataKi:  199nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKi:  225nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056127(CHEMBL3322142)
Affinity DataKi:  328nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056135(CHEMBL3322161)
Affinity DataKi:  1.94E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataKi:  2.09E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataKi:  6.34E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataKi:  6.53E+4nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056135(CHEMBL3322161)
Affinity DataKi:  9.28E+4nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed