Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50006220
LigandPNGBDBM50169425(US9481677, 44 | CHEMBL3341983)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Nav1.7 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM275868(US10071957, Example 87)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Nav1.7 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM258159(US9493448, 61 | US9845313, Example 61)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50024245(CHEMBL3325524)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Nav1.7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM145227(US8952169, 6 | US9771376, Example 6)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Nav1.7 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497931(CHEMBL3341986)
Affinity DataIC50: 4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM154456(US9012443, 521)
Affinity DataIC50: 19nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 30nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497937(CHEMBL3341976)
Affinity DataIC50: 35nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM170190(US9079902, 21)
Affinity DataIC50: 38nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM231255(US9346798, 2)
Affinity DataIC50: 39nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497932(CHEMBL3341989)
Affinity DataIC50: 67nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497939(CHEMBL3341974)
Affinity DataIC50: 127nMAssay Description:Inhibition of human Nav1 .8 expressed in HEK cells by PatchXpress electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497930(CHEMBL3341978)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM264714((R)-1-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-...)
Affinity DataIC50: 133nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50393023(CHEMBL2152688)
Affinity DataIC50: 140nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM185975(US9163008, 64 | US9656968, Compound 64)
Affinity DataIC50: 180nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497928(CHEMBL3341975)
Affinity DataIC50: 190nMAssay Description:Inhibition of human Nav1 .8 expressed in HEK cells by PatchXpress electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50393029(CHEMBL2152694)
Affinity DataIC50: 237nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497929(CHEMBL3341977)
Affinity DataIC50: 240nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM190561(US9181185, 19 | US9624194, Compound 19)
Affinity DataIC50: 244nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497934(CHEMBL3341996)
Affinity DataIC50: 398nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as half-maximal voltage for steady state inactivation by QPatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497933(CHEMBL3341995)
Affinity DataIC50: 620nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497926(CHEMBL3341994)
Affinity DataIC50: 770nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM236497(US9388137, 1)
Affinity DataIC50: 872nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50169425(US9481677, 44 | CHEMBL3341983)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM145227(US8952169, 6 | US9771376, Example 6)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497940(CHEMBL3341993)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM275868(US10071957, Example 87)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin) by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497927(CHEMBL3341997)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as half-maximal voltage for steady state inactivation by QPatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497941(CHEMBL3342000)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497936(CHEMBL3342001)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497935(CHEMBL3341999)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497938(CHEMBL3341998)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as half-maximal voltage for steady state inactivation by QPatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM154456(US9012443, 521)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM231255(US9346798, 2)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50024245(CHEMBL3325524)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM170190(US9079902, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM185975(US9163008, 64 | US9656968, Compound 64)
Affinity DataKi:  16nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50393023(CHEMBL2152688)
Affinity DataKi:  19nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497932(CHEMBL3341989)
Affinity DataKi:  27nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM190561(US9181185, 19 | US9624194, Compound 19)
Affinity DataKi:  347nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM236497(US9388137, 1)
Affinity DataKi:  6.03E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed