Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50044055
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005021(CHEMBL2408786 | US9650336, Example 3)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as release of sAPPbeta after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005019(CHEMBL2408785 | US9650336, Example 4)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as release of sAPPbeta after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005022(CHEMBL2408787 | US9650336, Example 1)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as release of sAPPbeta after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005021(CHEMBL2408786 | US9650336, Example 3)
Affinity DataIC50: 18nMAssay Description:Inhibition of human BACE1 cloned in HEK293 cells using Eu-CEVNLDAEFK-QSY 7 as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005022(CHEMBL2408787 | US9650336, Example 1)
Affinity DataIC50: 22nMAssay Description:Inhibition of human BACE1 cloned in HEK293 cells using Eu-CEVNLDAEFK-QSY 7 as substrate preincubated for 10 mins followed by substrate addition under...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005020(CHEMBL2408784 | US9650336, Example 9)
Affinity DataIC50: 168nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells assessed as release of sAPPbeta after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005019(CHEMBL2408785 | US9650336, Example 4)
Affinity DataIC50: 258nMAssay Description:Inhibition of human BACE1 cloned in HEK293 cells using Eu-CEVNLDAEFK-QSY 7 as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50005020(CHEMBL2408784 | US9650336, Example 9)
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of human BACE1 cloned in HEK293 cells using Eu-CEVNLDAEFK-QSY 7 as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed