Compile Data Set for Download or QSAR
Report error Found 129 Enz. Inhib. hit(s) with all data for entry = 50039807
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384482(CHEMBL2036207)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384475(CHEMBL2036225)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384484(CHEMBL2036029)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384461(CHEMBL2036215)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384464(CHEMBL2036210)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384464(CHEMBL2036210)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384482(CHEMBL2036207)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change incubated for 20 mins prior...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384467(CHEMBL2036213)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384475(CHEMBL2036225)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384467(CHEMBL2036213)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384472(CHEMBL2036220)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384474(CHEMBL2036223)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384483(CHEMBL2036026)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384476(CHEMBL2036217)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384464(CHEMBL2036210)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384472(CHEMBL2036220)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384475(CHEMBL2036225)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384467(CHEMBL2036213)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384474(CHEMBL2036223)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384469(CHEMBL2036017)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384464(CHEMBL2036210)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384475(CHEMBL2036225)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384469(CHEMBL2036017)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384470(CHEMBL2036030)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384470(CHEMBL2036030)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384471(CHEMBL2036203)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384471(CHEMBL2036203)
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384471(CHEMBL2036203)
Affinity DataIC50: 680nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384469(CHEMBL2036017)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384470(CHEMBL2036030)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384476(CHEMBL2036217)
Affinity DataIC50: 970nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384476(CHEMBL2036217)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384476(CHEMBL2036217)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384474(CHEMBL2036223)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384461(CHEMBL2036215)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384462(CHEMBL2036208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384463(CHEMBL2036209)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384464(CHEMBL2036210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384465(CHEMBL2036211)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384466(CHEMBL2036212)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384467(CHEMBL2036213)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384468(CHEMBL2036214)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384461(CHEMBL2036215)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2B6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384461(CHEMBL2036215)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2B6 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384462(CHEMBL2036208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384463(CHEMBL2036209)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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