Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50044475
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 57nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 700nMAssay Description:Inhibition of MAO-A in rat liver homogenate preincubated for 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate preincubated for 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018672(CHEMBL3291020)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018672(CHEMBL3291020)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018673(CHEMBL3291018)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018674(CHEMBL3291017)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018674(CHEMBL3291017)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018674(CHEMBL3291017)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018674(CHEMBL3291017)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018675(CHEMBL3291016)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018673(CHEMBL3291018)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018675(CHEMBL3291016)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018675(CHEMBL3291016)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018672(CHEMBL3291020)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 3.95E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018673(CHEMBL3291018)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018675(CHEMBL3291016)
Affinity DataIC50: 8.54E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataKi:  1.21E+3nMAssay Description:Reversible inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed