Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50043961
TargetSmoothened homolog(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50: 20nMAssay Description:Inhibition of smoothened (unknown origin)-mediated Shh signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at smoothened (unknown origin) expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50449053(CHEMBL3126707)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at smoothened (unknown origin) expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50449054(CHEMBL3126705)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at smoothened (unknown origin) expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50449052(CHEMBL3126692)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at smoothened (unknown origin) expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed