Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50043450
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of GAT-1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EAAT2 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of GlyT1 (unknown origin) expressed in MDCK cells using [3H]-glycine as substrate after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of EAAT3 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of EAAT1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50218812((3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of GAT-3 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed