Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 7730
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Human)
The Scripps Research Institute

LigandPNGBDBM50112347(CHEMBL3609327 | FRAX597)
Affinity DataIC50: 7.70nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 2(Human)
The Scripps Research Institute

LigandPNGBDBM50112347(CHEMBL3609327 | FRAX597)
Affinity DataIC50: 12.8nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 3(Human)
The Scripps Research Institute

LigandPNGBDBM50112347(CHEMBL3609327 | FRAX597)
Affinity DataIC50: 19.3nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Human)
The Scripps Research Institute

LigandPNGBDBM213235(FRAX414)
Affinity DataIC50: 20nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Human)
The Scripps Research Institute

LigandPNGBDBM6276(Pyrido[2,3-d]pyrimidin-7-one 1 | 8-Cyclopentyl-2-[...)
Affinity DataIC50: 483nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
The Scripps Research Institute

LigandPNGBDBM213235(FRAX414)
Affinity DataIC50: 559nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
The Scripps Research Institute

LigandPNGBDBM6276(Pyrido[2,3-d]pyrimidin-7-one 1 | 8-Cyclopentyl-2-[...)
Affinity DataIC50: 580nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
The Scripps Research Institute

LigandPNGBDBM50112347(CHEMBL3609327 | FRAX597)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details Article
PubMed