Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50043343
TargetOrexin receptor type 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50439587(CHEMBL2418879)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at OX2 receptor (unknown origin) expressed in RD-HGA16 cells assessed as calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50439587(CHEMBL2418879)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at OX1 receptor (unknown origin) expressed in RD-HGA16 cells assessed as calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at OX1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL291536 | CHEMBL2111553 | SB-334867)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at OX1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOrexin/Hypocretin receptor type 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50292929(almorexant | CHEMBL455136)
Affinity DataIC50: 119nMAssay Description:Antagonist activity at OX1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50438822(CHEMBL2413367)
Affinity DataIC50: 417nMAssay Description:Antagonist activity at OX2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50292929(almorexant | CHEMBL455136)
Affinity DataIC50: 8.10E+3nMAssay Description:Antagonist activity at OX2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed