Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50043360
LigandPNGBDBM50305083(Ko143 | Ko-143 | 3-((3S,6S)-6-Isobutyl-9-methoxy-1...)
Affinity DataIC50: 215nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50305083(Ko143 | Ko-143 | 3-((3S,6S)-6-Isobutyl-9-methoxy-1...)
Affinity DataIC50: 354nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50439852(CHEMBL2420091)
Affinity DataIC50: 426nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439851(CHEMBL2420084)
Affinity DataIC50: 457nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439850(CHEMBL2420094)
Affinity DataIC50: 458nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439852(CHEMBL2420091)
Affinity DataIC50: 468nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439851(CHEMBL2420084)
Affinity DataIC50: 522nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50338974(2-(3,4-Dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-c...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50338974(2-(3,4-Dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-c...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439850(CHEMBL2420094)
Affinity DataIC50: 590nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439846(CHEMBL2420087)
Affinity DataIC50: 724nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50404748(NSC-115922 | CHEMBL19032)
Affinity DataIC50: 822nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50064895(2-(3,4-Dimethoxy-phenyl)-3-hydroxy-7-methoxy-chrom...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439838(CHEMBL2420090)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439845(CHEMBL2420083)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439847(CHEMBL2420103)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439844(FISETIN TETRAMETHYL ETHER)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439849(CHEMBL144625)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439845(CHEMBL2420083)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439849(CHEMBL144625)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439848(CHEMBL2420082)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439848(CHEMBL2420082)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439847(CHEMBL2420103)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439846(CHEMBL2420087)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439840(CHEMBL2420085)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439842(CHEMBL2420093)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50439845(CHEMBL2420083)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in human 2008 cells assessed as calcein-AM accumulation preincubated for 30 mins before calcein-AM addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50064895(2-(3,4-Dimethoxy-phenyl)-3-hydroxy-7-methoxy-chrom...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50404748(NSC-115922 | CHEMBL19032)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439844(FISETIN TETRAMETHYL ETHER)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439841(CHEMBL2420089)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439843(CHEMBL2420092)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439842(CHEMBL2420093)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439841(CHEMBL2420089)
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in human 2008 cells assessed as calcein-AM accumulation preincubated for 30 mins before calcein-AM addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439840(CHEMBL2420085)
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439839(CHEMBL2420099)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439838(CHEMBL2420090)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439837(MORIN PENTAMETHYL ETHER)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439837(MORIN PENTAMETHYL ETHER)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439843(CHEMBL2420092)
Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439861(CHEMBL2420100)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439860(CHEMBL2420097)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439859(CHEMBL2420086)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50439861(CHEMBL2420100)
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50049399(2-(2,4-Dimethoxy-phenyl)-3,5,7-trimethoxy-chromen-...)
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50049399(2-(2,4-Dimethoxy-phenyl)-3,5,7-trimethoxy-chromen-...)
Affinity DataIC50: 5.98E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50028963(beta-naphthoflavone | 3-phenyl-1H-benzo[f]chromen-...)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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