Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50043250
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM51911(3-(2-methoxyphenyl)-3-(4-methoxyphenyl)-N-[(4-prop...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM51911(3-(2-methoxyphenyl)-3-(4-methoxyphenyl)-N-[(4-prop...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM51911(3-(2-methoxyphenyl)-3-(4-methoxyphenyl)-N-[(4-prop...)
Affinity DataIC50: 660nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-14(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM51911(3-(2-methoxyphenyl)-3-(4-methoxyphenyl)-N-[(4-prop...)
Affinity DataIC50: 970nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50: 990nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-14(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-14(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-7(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50438170(CHEMBL2407437)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33453((3-Amino-[1,2,4]triazol-4-yl)-(4-methoxy-phenyl)-m...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM50438170(CHEMBL2407437)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-14(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-14(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33882(SMR000306508 | (5-azanyl-3-pyridin-3-yl-1,2,4-tria...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM33437(MLS000099650 | SMR000074479 | 1-(3,4-dimethoxybenz...)
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-5 [D153N](Human)
Pierre and Marie Curie University

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed