Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50005455
TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50492250(CHEMBL2398178)
Affinity DataEC50:  1.31E+3nMAssay Description:Inhibition of p-gp in human KB/VCR cells assessed as potentiation of 100 nM docetaxel-induced cytotoxicity after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataEC50:  1.25E+3nMAssay Description:Inhibition of p-gp in human KB/VCR cells assessed as potentiation of 100 nM docetaxel-induced cytotoxicity after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50492251(CHEMBL2398097)
Affinity DataEC50:  1.37E+3nMAssay Description:Inhibition of p-gp in human KB/VCR cells assessed as potentiation of 100 nM docetaxel-induced cytotoxicity after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed