Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50042957
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433763(CHEMBL2381611)
Affinity DataIC50: 18nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433766(CHEMBL2381604)
Affinity DataIC50: 23nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433765(CHEMBL2381605)
Affinity DataIC50: 27nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433758(CHEMBL2381596)
Affinity DataIC50: 39nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433760(CHEMBL2381599)
Affinity DataIC50: 290nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433768(CHEMBL2381602)
Affinity DataIC50: 310nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433769(CHEMBL2381600)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433758(CHEMBL2381596)
Affinity DataIC50: 650nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433759(CHEMBL2381598)
Affinity DataIC50: 690nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433767(CHEMBL2381603)
Affinity DataIC50: 820nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433763(CHEMBL2381611)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433769(CHEMBL2381600)
Affinity DataIC50: 890nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433765(CHEMBL2381605)
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433766(CHEMBL2381604)
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CAMK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human IRAK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433768(CHEMBL2381602)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433762(CHEMBL2381612)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433764(CHEMBL2381607)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433760(CHEMBL2381599)
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433759(CHEMBL2381598)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433767(CHEMBL2381603)
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433770(CHEMBL2381597)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase I isoform delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human CSNK1DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTestis-specific serine/threonine-protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human TSSK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human JAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human IKKBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433773(CHEMBL2381608)
Affinity DataIC50: 4.21E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433771(CHEMBL2381610)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433772(CHEMBL2381609)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433764(CHEMBL2381607)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed