Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50042880
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50432593(CHEMBL2347183)
Affinity DataIC50: 130nMAssay Description:Inhibition of C-terminal His-tagged wild type CYP3A4 (unknown origin)-mediated hydroxylation of 7-benzyloxy-4-trifluoromethylcoumarin expressed in Es...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50432595(CHEMBL2347185)
Affinity DataIC50: 280nMAssay Description:Inhibition of C-terminal His-tagged wild type CYP3A4 (unknown origin)-mediated hydroxylation of 7-benzyloxy-4-trifluoromethylcoumarin expressed in Es...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM520(ABT-538 | Norvir | CHEMBL163 | 1,3-thiazol-5-ylmet...)
Affinity DataIC50: 550nMAssay Description:Inhibition of C-terminal His-tagged wild type CYP3A4 (unknown origin)-mediated hydroxylation of 7-benzyloxy-4-trifluoromethylcoumarin expressed in Es...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50432594(CHEMBL2347184)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of C-terminal His-tagged wild type CYP3A4 (unknown origin)-mediated hydroxylation of 7-benzyloxy-4-trifluoromethylcoumarin expressed in Es...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)