Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 6045
TargetHistone deacetylase 3(Human)
Shandong University

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 28.4nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50: 37.6nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 75.6nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50: 87.7nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 118nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50: 175nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 256nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50: 675nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed