Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50042836
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431891(CHEMBL2347651)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50: 6nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431890(CHEMBL2347656)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431892(CHEMBL2347652)
Affinity DataIC50: 40nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431889(CHEMBL2347653)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431888(CHEMBL2347654)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50330550(N-(4-chlorophenyl)-2,7,7-trimethyl-5-oxo-4-phenyl-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772(STLC | Tritylcysteine | 3-Tritylthio-L-alanine | N...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human Eg5 catalytic domain assessed as inhibition of microtubulin-induced ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50323769((4S)-4-(3-HYDROXYPHENYL)-7,7-DIMETHYL-2-THIOXO-2,3...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431887(CHEMBL2347798)
Affinity DataIC50: 350nMAssay Description:Inhibition of human His-tagged Eg5 (1 to 368 amino acid residues) basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 520nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431884(CHEMBL2347649)
Affinity DataIC50: 650nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50198301((3aS,10R)-2-butyl-10-(3-hydroxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM23772(STLC | Tritylcysteine | 3-Tritylthio-L-alanine | N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Eg5 catalytic domain basal ATPase activity after 25 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Eg5 in human HCT116 cells assessed as inhibition of microtubule-induced ATPase activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50323768((S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAH...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50192334(adociasulfate-2 | CHEMBL426141)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50192334(adociasulfate-2 | CHEMBL426141)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human recombinant Eg5 ATPase activity expressed in Escherichia coli after 30 mins by malachite green-based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431885(TERPENDOLE E)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human Eg5 assessed as inhibition of microtubule-induced ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50431885(TERPENDOLE E)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50216502(monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed