Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50042829
TargetPlatelet-derived growth factor receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDGFRbeta (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of p70S6K (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of PKC alpha (unknown origin) using PIP2 as substrate after 1 hr by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDGFRalpha (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Aurora B (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of LCK (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 4nMAssay Description:Inhibition of LYNA (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 4nMAssay Description:Inhibition of MSK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of KDR (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of SRC (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PDK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 10nMAssay Description:Inhibition of cKit (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alpha (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 11nMAssay Description:Inhibition of AKT1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 12nMAssay Description:Inhibition of FGFR1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 13nMAssay Description:Inhibition of GSK3beta (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50248765(1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrol...)
Affinity DataIC50: 15nMAssay Description:Inhibition of His6x-tagged RSK2 C-terminal domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 25nMAssay Description:Inhibition of FGFR3 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 54nMAssay Description:Inhibition of PIM1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 89nMAssay Description:Inhibition of GST-fused RSK2 (unknown origin) after 10 to 45 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 109nMAssay Description:Inhibition of c-MET (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 271nMAssay Description:Inhibition of ABL (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 500nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of ERK1 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431814(CHEMBL2347075)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431810(CHEMBL2347061)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431815(CHEMBL2347074)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431813(CHEMBL2347085)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50344214(3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431816(CHEMBL2347073)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431812(CHEMBL2347053)
Affinity DataIC50: 5.03E+3nMAssay Description:Inhibition of JNK2 (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431816(CHEMBL2347073)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431811(CHEMBL2347054)
Affinity DataIC50: 8.59E+3nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431809(CHEMBL2347062)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed