Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50042545
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427608(CHEMBL2322943)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427614(CHEMBL2322946)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)
Affinity DataEC50:  1.59E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427613(CHEMBL2322935)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427612(CHEMBL2322942)
Affinity DataEC50:  5.35E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427611(CHEMBL2322939)
Affinity DataEC50:  6.18E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427610(CHEMBL2322940)
Affinity DataEC50:  6.69E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427609(CHEMBL2322941)
Affinity DataEC50:  9.93E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427601(CHEMBL2322938)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427607(CHEMBL2322944)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427606(CHEMBL2322945)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427605(CHEMBL2322932)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427604(CHEMBL2322936)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50032964(4-Amino-3-(4-chloro-phenyl)-butyric acid | (R)-4-A...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)
Affinity DataEC50:  3.78E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)
Affinity DataEC50:  3.78E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427602(CHEMBL2322937)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed