Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50042650
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50: 0.0620nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50: 0.0760nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148201(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MMP2 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50106136(2-{[4-(4-Chloro-phenoxy)-benzenesulfonyl]-methyl-a...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50428828(CHEMBL2337131)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095222(N-hydroxy-2-(4-(4-(trifluoromethyl)phenoxy)piperid...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24043((2R)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095218(N-Hydroxy-2-[4-(4-trifluoromethoxy-phenoxy)-piperi...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50428829(CHEMBL2337130)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075(CHEMBL43152 | (2S)-2-{[4-(4-bromophenyl)benzene]su...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075(CHEMBL43152 | (2S)-2-{[4-(4-bromophenyl)benzene]su...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50428829(CHEMBL2337130)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MMP9 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096477(3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 15nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095222(N-hydroxy-2-(4-(4-(trifluoromethyl)phenoxy)piperid...)
Affinity DataIC50: 28nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095218(N-Hydroxy-2-[4-(4-trifluoromethoxy-phenoxy)-piperi...)
Affinity DataIC50: 33nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 34nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075(CHEMBL43152 | (2S)-2-{[4-(4-bromophenyl)benzene]su...)
Affinity DataIC50: 47nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096477(3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 47nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096476((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-c...)
Affinity DataIC50: 174nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096476((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-c...)
Affinity DataIC50: 181nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096476((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-c...)
Affinity DataIC50: 233nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096480(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-5-bro...)
Affinity DataIC50: 236nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075(CHEMBL43152 | (2S)-2-{[4-(4-bromophenyl)benzene]su...)
Affinity DataIC50: 240nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096480(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-5-bro...)
Affinity DataIC50: 427nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096480(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-5-bro...)
Affinity DataIC50: 639nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096477(3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMatrix metalloproteinase-9(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed