Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50042489
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50393756(CHEMBL2159198)
Affinity DataEC50:  6.60E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426736(CHEMBL2322139)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426735(CHEMBL2322141)
Affinity DataEC50:  1.58E+4nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426734(CHEMBL2322142)
Affinity DataEC50:  4.80E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426733(CHEMBL2322143)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426732(CHEMBL2322134)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426734(CHEMBL2322142)
Affinity DataEC50:  150nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50393756(CHEMBL2159198)
Affinity DataEC50:  180nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426735(CHEMBL2322141)
Affinity DataEC50:  350nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426731(CHEMBL2322138 | 1-cyclohexyl-1,6-dihydroimidazo[4,...)
Affinity DataEC50:  9.80E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426732(CHEMBL2322134)
Affinity DataEC50:  370nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataEC50:  890nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataEC50:  430nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataEC50:  170nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426736(CHEMBL2322139)
Affinity DataEC50:  970nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426731(CHEMBL2322138 | 1-cyclohexyl-1,6-dihydroimidazo[4,...)
Affinity DataEC50:  210nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426734(CHEMBL2322142)
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426732(CHEMBL2322134)
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426733(CHEMBL2322143)
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50393756(CHEMBL2159198)
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426731(CHEMBL2322138 | 1-cyclohexyl-1,6-dihydroimidazo[4,...)
Affinity DataIC50: 30nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426735(CHEMBL2322141)
Affinity DataIC50: 30nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426733(CHEMBL2322143)
Affinity DataIC50: 30nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataIC50: 30nMAssay Description:Inhibition of JAK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426734(CHEMBL2322142)
Affinity DataIC50: 40nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426736(CHEMBL2322139)
Affinity DataIC50: 40nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataIC50: 50nMAssay Description:Inhibition of TYK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataIC50: 50nMAssay Description:Inhibition of JAK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataIC50: 60nMAssay Description:Inhibition of TYK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426735(CHEMBL2322141)
Affinity DataIC50: 90nMAssay Description:Inhibition of JAK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataIC50: 90nMAssay Description:Inhibition of KDR (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataIC50: 90nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataIC50: 130nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426733(CHEMBL2322143)
Affinity DataIC50: 150nMAssay Description:Inhibition of FLT3 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataIC50: 160nMAssay Description:Inhibition of KDR (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataIC50: 200nMAssay Description:Inhibition of KDR (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426739(CHEMBL2322135)
Affinity DataIC50: 220nMAssay Description:Inhibition of FLT3 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426734(CHEMBL2322142)
Affinity DataIC50: 240nMAssay Description:Inhibition of FLT3 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426732(CHEMBL2322134)
Affinity DataIC50: 270nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataIC50: 300nMAssay Description:Inhibition of TYK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataIC50: 340nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426738(CHEMBL2322136)
Affinity DataIC50: 440nMAssay Description:Inhibition of FLT3 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426740(CHEMBL2322140)
Affinity DataIC50: 530nMAssay Description:Inhibition of TYK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 1 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50426737(CHEMBL2322137)
Affinity DataIC50: 570nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Displayed 1 to 50 (of 78 total ) | Next | Last >>
Jump to: