Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50042370
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424964(CHEMBL2316151 | US9409845, Table 1, Compound 12: (...)
Affinity DataIC50: 400nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424973(CHEMBL2316142 | US9409845, Table 1, Compound 3: (2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424975(CHEMBL2316140 | US9409845, Table 1, Compound 1: (2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424957(CHEMBL2316158 | US9409845, Table 1, Compound 19: (...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424958(CHEMBL2316157 | US9409845, Table 1, Compound 18: (...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424972(CHEMBL2316143 | US9409845, Table 1, Compound 4: (2...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424974(CHEMBL2316141 | US9409845, Table 1, Compound 2: (2...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424961(CHEMBL2316154 | US9409845, Table 1, Compound 15: (...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424962(CHEMBL2316153 | US9409845, Table 1, Compound 14: (...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424956(CHEMBL2316159 | US9409845, Table 1, Compound 20: (...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424960(CHEMBL2316155 | US9409845, Table 1, Compound 16: (...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424968(CHEMBL2316147 | US9409845, Table 1, Compound 8: (2...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424965(CHEMBL2316150 | US9409845, Table 1, Compound 11: (...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424970(CHEMBL2316145 | US9409845, Table 1, Compound 6: (2...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424969(CHEMBL2316146 | US9409845, Table 1, Compound 7: (2...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424966(CHEMBL2316149 | US9409845, Table 1, Compound 10: (...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424971(CHEMBL2316144 | US9409845, Table 1, Compound 5: (2...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50067040(CHEMBL116438 | 1,7-bis(4-hydroxy-3-methoxyphenyl)1...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424967(CHEMBL2316148 | US9409845, Table 1, Compound 9: (2...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424959(CHEMBL2316156)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424963(CHEMBL2316152 | US9409845, Table 1, Compound 13: (...)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed