Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50040921
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402202(CHEMBL2203964)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402204(CHEMBL2203978)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402206(CHEMBL2203976)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402207(CHEMBL2203975)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402203(CHEMBL2203963)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402208(CHEMBL2203974)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402200(CHEMBL2203966)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402201(CHEMBL2203965)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402205(CHEMBL2203977)
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402199(CHEMBL2203967)
Affinity DataIC50: 510nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402215(CHEMBL1624076)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50241121(S-p-bromobenzyl glutatione | S-p-bromobenzylglutat...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402214(CHEMBL2203968)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402212(CHEMBL2203970)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402213(CHEMBL2203969)
Affinity DataIC50: 8.28E+3nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402211(CHEMBL2203971)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402209(CHEMBL2203973)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402210(CHEMBL2203972)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed