Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50045938
TargetCytochrome P450 1A2(Human)
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Onyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088506(CHEMBL3542249)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed