Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50040454
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataKd:  0.0230nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50394444(CHEMBL2159649)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry/ fluorimetric titration analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50214707(9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguani...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry/ fluorimetric titration analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50214705(9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...)
Affinity DataKd:  0.460nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry/ fluorimetric titration analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50108005(9-DEAZAGUANINE | 2-Amino-3,5-dihydro-pyrrolo[3,2-d...)
Affinity DataKd:  170nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by fluorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50108005(9-DEAZAGUANINE | 2-Amino-3,5-dihydro-pyrrolo[3,2-d...)
Affinity DataKd:  160nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50200094(2-amino-1,9-dihydro-6H-purin-6-one | guanine | Gua...)
Affinity DataKd:  160nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by fluorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50200094(2-amino-1,9-dihydro-6H-purin-6-one | guanine | Gua...)
Affinity DataKd:  120nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)
Affinity DataKd:  680nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50214707(9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguani...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of bovine PNP using 7-methylguanosine as substrate by spectrophotometric based coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(Bovine)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50394443(CHEMBL2159650)
Affinity DataKi:  63nMAssay Description:Inhibition of bovine PNP using 7-methylguanosine as substrate by spectrophotometric based coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed