Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50040311
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392443(CHEMBL2151810)
Affinity DataEC50:  297nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50337958(N-cyclobutyl-6-((3-fluorophenyl)ethynyl)nicotinami...)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392441(CHEMBL2151808)
Affinity DataEC50:  3.80E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392442(CHEMBL2151809)
Affinity DataEC50:  1.62E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392443(CHEMBL2151810)
Affinity DataEC50:  295nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392444(CHEMBL2151811)
Affinity DataEC50:  302nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392445(CHEMBL2151813)
Affinity DataEC50:  135nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392446(CHEMBL2151814)
Affinity DataEC50:  166nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392447(CHEMBL2151815)
Affinity DataEC50:  15.1nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392448(CHEMBL2151816)
Affinity DataEC50:  85.1nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50:  7.24nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392439(CHEMBL2151806)
Affinity DataEC50:  29nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392440(CHEMBL2151807)
Affinity DataEC50:  251nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392441(CHEMBL2151808)
Affinity DataEC50:  3.81E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392442(CHEMBL2151809)
Affinity DataEC50:  1.60E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392440(CHEMBL2151807)
Affinity DataEC50:  251nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392444(CHEMBL2151811)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392445(CHEMBL2151813)
Affinity DataEC50:  136nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392446(CHEMBL2151814)
Affinity DataEC50:  167nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392447(CHEMBL2151815)
Affinity DataEC50:  15nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392448(CHEMBL2151816)
Affinity DataEC50:  83nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50:  7.20nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR7More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392438(CHEMBL2151805)
Affinity DataEC50:  34nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392425(CHEMBL2151790)
Affinity DataEC50:  33nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392426(CHEMBL2151791)
Affinity DataEC50:  603nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392427(CHEMBL2151792)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392428(CHEMBL2151793)
Affinity DataEC50:  5.13E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392429(CHEMBL2151795)
Affinity DataEC50:  724nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392430(CHEMBL2151796)
Affinity DataEC50:  2.51E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392431(CHEMBL2151797)
Affinity DataEC50:  1.91E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392426(CHEMBL2151791)
Affinity DataEC50:  607nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392427(CHEMBL2151792)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392428(CHEMBL2151793)
Affinity DataEC50:  5.17E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392429(CHEMBL2151795)
Affinity DataEC50:  725nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392430(CHEMBL2151796)
Affinity DataEC50:  2.49E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392431(CHEMBL2151797)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392433(CHEMBL2151818)
Affinity DataEC50:  180nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392434(CHEMBL2151798)
Affinity DataEC50:  447nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392435(CHEMBL2151801)
Affinity DataEC50:  1.07E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392436(CHEMBL2151802)
Affinity DataEC50:  1.15E+3nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392437(CHEMBL2151804)
Affinity DataEC50:  447nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392438(CHEMBL2151805)
Affinity DataEC50:  33.9nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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