Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50040549
Affinity DataKd: 164nMAssay Description:Binding affinity to human recombinant G9a catalytic domain amino acid 913 to 1193 expressed in Escherichia coli BL21 (DE3) by isothermal titration ca...More data for this Ligand-Target Pair
Affinity DataKd: 136nMAssay Description:Binding affinity to human recombinant GLP catalytic domain amino acid 951 to 1235 expressed in Escherichia coli BL21 (DE3) by isothermal titration ca...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant DOT1L using [3H]-SAM as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Competitive inhibition of GLP by fluorescence polarization assay in presence of fluorescein-labeled H3 peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of G9a in human MCF7 cells after 48 hrs by clonogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells after 48 hrs by clonogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of JMJD2E catalytic domain by mass spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of GST-tagged human DOT1L amino acid 1 to 472 expressed in Escherichia coli BL21 (DE3) using [3H]-SAM as substrate preincubated for 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of GST-tagged human DOT1L amino acid 1 to 472 expressed in Escherichia coli BL21 (DE3) using [3H]-SAM as substrate preincubated for 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of full length human SMYD2 amino acid 1 to 433 expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl- GSRAHSSHLKSKKGQSTSRH as...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of JMJD2E catalytic domain by mass spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of SUV39H1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of full length N-terminal 6x His-tagged human LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate by luminol ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of full length N-terminal 6x His-tagged human LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate by luminol ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of full length N-terminal 6x His-tagged human LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate by luminol ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of full length N-terminal 6x His-tagged human LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate by luminol ...More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of SUV39H1More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant Drosophila melanogaster SUV39 by radioactive filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged GLP SET domain amino acid 951 to 1235 expressed in Escherichia coli BL21 (DE3) using Histone H3 p...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human SUV39H1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant G9a catalytic domain amino acid 913 to 1193 expressed in Escherichia coli BL21 (DE3) by mass spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of GST-tagged G9a after 1 hr by radioactive filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of JMJD2A catalytic domain by mass spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human N-terminal hexahistidine-tagged G9a SET domain amino acid 913 to 1193 expressed in Escherichia coli BL21 (DE3) using Histone H3 p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N terminal hexahistidine-tag recombinant human LSD1 expressed in Escherichia coli BL21 (DE3) using histone H3 peptide as substrate prei...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of JMJD2E catalytic domain by mass spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of GST-tagged G9a after 1 hr by radioactive filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of mouse G9aMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N terminal hexahistidine-tag recombinant human LSD1 expressed in Escherichia coli BL21 (DE3) using histone H3 peptide as substrate prei...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human JMJD2EMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of N-terminal GST-fused human JMJD2C catalytic domain amino acid 1 to 420 using H3K9me3 as substrate by mass spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of JMJD2AMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9aMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SUV39H1More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST-tagged G9a after 1 hr by radioactive filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of Drosophila melanogaster E(Z)More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of Drosophila melanogaster PRSET7More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of G9a using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV39H1 using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT1 using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CARM1 expressed in Escherichia coli BL21 (DE3) using [3H]-SAM as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT1 using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of G9a using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV39H1 using [3H]-SAM as substrate preincubated for 10 mins before substrate addition measured after 30 mins by scintillation counterMore data for this Ligand-Target Pair
