Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50040698
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50398565(CHEMBL2179195)
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398579(CHEMBL2179182)
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50398587(CHEMBL2179197 | US8530504, 4)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398566(CHEMBL2179196)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398580(CHEMBL2179181)
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398578(CHEMBL2179183 | US8530504, 27)
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398582(CHEMBL2179179)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398573(CHEMBL2179188)
Affinity DataIC50: 52nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398583(CHEMBL2179178)
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398568(CHEMBL2179193)
Affinity DataIC50: 63nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398570(CHEMBL2179191)
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398585(CHEMBL2179176)
Affinity DataIC50: 69nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398565(CHEMBL2179195)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398581(CHEMBL2179180)
Affinity DataIC50: 75nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398586(CHEMBL2177105 | US8530504, 5)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398574(CHEMBL2179187)
Affinity DataIC50: 83nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398571(CHEMBL2179190)
Affinity DataIC50: 91nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398575(CHEMBL2179186)
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398577(CHEMBL2179184)
Affinity DataIC50: 101nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398569(CHEMBL2179192)
Affinity DataIC50: 126nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398572(CHEMBL2179189)
Affinity DataIC50: 136nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398576(CHEMBL2179185)
Affinity DataIC50: 147nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398584(CHEMBL2179177)
Affinity DataIC50: 223nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398567(CHEMBL2179194)
Affinity DataIC50: 254nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398565(CHEMBL2179195)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2 receptor assessed as inhibition of CRF-induced intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed