Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50040120
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389432(CHEMBL2064618)
Affinity DataKd:  1.73nMAssay Description:Binding affinity to VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma counting in presence of haloperidolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389434(CHEMBL2064619)
Affinity DataKd:  17.4nMAssay Description:Binding affinity to VAChT in rat cerebral membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50009602(CHEMBL89298 | 2-(4-Phenyl-piperidin-1-yl)-cyclohex...)
Affinity DataKd:  7.40nMAssay Description:Binding affinity to VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma counting in presence of DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.5nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cerebral membrane after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389433(CHEMBL2064616)
Affinity DataKi:  9.30nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389435(CHEMBL2064617)
Affinity DataKi:  13.6nMAssay Description:Displacement of (-)-[3H]vesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 60 mins by liquid scintillation counting in presence of DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389433(CHEMBL2064616)
Affinity DataKi:  13.8nMAssay Description:Displacement of (-)-[3H]vesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 60 mins by liquid scintillation counting in presence of DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389432(CHEMBL2064618)
Affinity DataKi:  20.5nMAssay Description:Displacement of (-)-[3H]vesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 60 mins by liquid scintillation counting in presence of DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataKi:  22.1nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cerebral membrane after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389432(CHEMBL2064618)
Affinity DataKi:  28.6nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataKi:  32.9nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataKi:  33.9nMAssay Description:Displacement of (-)-[3H]vesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 60 mins by liquid scintillation counting in presence of DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389435(CHEMBL2064617)
Affinity DataKi:  74.1nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cerebral membrane after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  131nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cerebral membrane after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389433(CHEMBL2064616)
Affinity DataKi:  151nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cerebral membrane after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50389432(CHEMBL2064618)
Affinity DataKi:  242nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cerebral membrane after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50010096(Hydroxy-diphenyl-acetic acid 1-aza-bicyclo[2.2.2]o...)
Affinity DataKi:  582nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  1.13E+3nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Rat)
Kanazawa University

Curated by ChEMBL
LigandPNGBDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]O-iodo-trans-decalinvesamicol from VAChT in Sprague-Dawley rat cerebral membrane after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed