Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50039986
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387328(CHEMBL2046649)
Affinity DataIC50: 5nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 52nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387349(CHEMBL2046644)
Affinity DataIC50: 58nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387346(CHEMBL2046640)
Affinity DataIC50: 165nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387350(CHEMBL2046646)
Affinity DataIC50: 229nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387352(CHEMBL2046648)
Affinity DataIC50: 410nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387354(CHEMBL2046651)
Affinity DataIC50: 410nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ITKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ZAP70More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of c-RafMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PKCtheta-mediated IL-2 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387328(CHEMBL2046649)
Affinity DataKi:  0.600nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387349(CHEMBL2046644)
Affinity DataKi:  2nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387346(CHEMBL2046640)
Affinity DataKi:  3nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataKi:  3nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387343(CHEMBL2046637)
Affinity DataKi:  4nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387348(CHEMBL2046642)
Affinity DataKi:  6nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387350(CHEMBL2046646)
Affinity DataKi:  7nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387328(CHEMBL2046649)
Affinity DataKi: <10nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387328(CHEMBL2046649)
Affinity DataKi:  10nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C epsilon type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataKi:  17nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387346(CHEMBL2046640)
Affinity DataKi:  20nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387352(CHEMBL2046648)
Affinity DataKi:  20nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387349(CHEMBL2046644)
Affinity DataKi:  22nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387354(CHEMBL2046651)
Affinity DataKi:  24nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataKi:  28nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387352(CHEMBL2046648)
Affinity DataKi:  30nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387333(CHEMBL2046626)
Affinity DataKi:  32nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataKi:  37nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387345(CHEMBL2046639)
Affinity DataKi:  38nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387349(CHEMBL2046644)
Affinity DataKi:  49nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387346(CHEMBL2046640)
Affinity DataKi:  54nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387341(CHEMBL2046635)
Affinity DataKi:  67nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387336(CHEMBL2046629)
Affinity DataKi:  76nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataKi:  76nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387342(CHEMBL2046636)
Affinity DataKi:  85nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387350(CHEMBL2046646)
Affinity DataKi:  87nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387354(CHEMBL2046651)
Affinity DataKi:  116nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387331(CHEMBL2046624)
Affinity DataKi:  164nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387340(CHEMBL2046634)
Affinity DataKi:  182nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387347(CHEMBL2046641)
Affinity DataKi:  238nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387329(CHEMBL2046645)
Affinity DataKi:  255nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387330(CHEMBL2046643)
Affinity DataKi:  260nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387344(CHEMBL2046638)
Affinity DataKi:  275nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387351(CHEMBL2046647)
Affinity DataKi:  290nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387332(CHEMBL2046625)
Affinity DataKi:  375nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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