Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50040854
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM18884(CHEMBL112087 | JMC496635 Compound 4 | 2-(4-{[4-hyd...)
Affinity DataKd:  35nMAssay Description:Antagonist activity at human TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM18884(CHEMBL112087 | JMC496635 Compound 4 | 2-(4-{[4-hyd...)
Affinity DataKd:  200nMAssay Description:Antagonist activity at human TRalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50401075(CHEMBL2203702)
Affinity DataEC50:  0.470nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM18920(2-[3,5-dichloro-4-(4-hydroxy-3-phenylphenoxy)pheny...)
Affinity DataEC50:  2.90nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50401075(CHEMBL2203702)
Affinity DataEC50:  18nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM18920(2-[3,5-dichloro-4-(4-hydroxy-3-phenylphenoxy)pheny...)
Affinity DataEC50:  152nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to human TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human TRalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  7.18nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50401076(CHEMBL457748)
Affinity DataKi:  600nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50401076(CHEMBL457748)
Affinity DataKi:  1.25E+4nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed