Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50039545
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379784(CHEMBL2011537)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379789(CHEMBL2011534)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379785(CHEMBL2011528)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379790(CHEMBL2011535)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant DPP4 using H-Gly-Pro-7-amino-4-methylcoumarin as substrate assessed as inhibition of 7-amino-4-methylcoumarin formati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379790(CHEMBL2011535)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379789(CHEMBL2011534)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DPP4 using H-Gly-Pro-7-amino-4-methylcoumarin as substrate assessed as inhibition of 7-amino-4-methylcoumarin formati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379785(CHEMBL2011528)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human recombinant DPP4 using H-Gly-Pro-7-amino-4-methylcoumarin as substrate assessed as inhibition of 7-amino-4-methylcoumarin formati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379789(CHEMBL2011534)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379785(CHEMBL2011528)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379789(CHEMBL2011534)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379788(CHEMBL2011533)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379785(CHEMBL2011528)
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379786(CHEMBL2011529)
Affinity DataIC50: 3.80E+3nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379787(CHEMBL2011532)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379789(CHEMBL2011534)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379785(CHEMBL2011528)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379790(CHEMBL2011535)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379790(CHEMBL2011535)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379784(CHEMBL2011537)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DPP4 using H-Gly-Pro-7-amino-4-methylcoumarin as substrate assessed as inhibition of 7-amino-4-methylcoumarin formati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379784(CHEMBL2011537)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379784(CHEMBL2011537)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379784(CHEMBL2011537)
Affinity DataKi:  6nMAssay Description:Antagonist activity at human MCH1R expressed in forskolin-stimulated CHO cells assessed as inhibition of MCH-induced cAMP accumulation after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM15517((3R,4R)-1-(6-phenylpyrimidin-4-yl)-4-(2,4,5-triflu...)
Affinity DataKi:  6nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed