Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50034608
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365165(CHEMBL1950017)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365164(CHEMBL1950016)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365157(CHEMBL1950009)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365161(CHEMBL1950013)
Affinity DataIC50: 16nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365168(CHEMBL1950020)
Affinity DataIC50: 19nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365167(CHEMBL1950019)
Affinity DataIC50: 31nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365162(CHEMBL1950014)
Affinity DataIC50: 40nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365160(CHEMBL1950012)
Affinity DataIC50: 42nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365164(CHEMBL1950016)
Affinity DataIC50: 66nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365164(CHEMBL1950016)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365158(CHEMBL1950010)
Affinity DataIC50: 128nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365166(CHEMBL1950018)
Affinity DataIC50: 128nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365165(CHEMBL1950017)
Affinity DataIC50: 150nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365165(CHEMBL1950017)
Affinity DataIC50: 150nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365157(CHEMBL1950009)
Affinity DataIC50: 155nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365159(CHEMBL1950011)
Affinity DataIC50: 414nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365163(CHEMBL1950015)
Affinity DataIC50: 421nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365169(CHEMBL1950021)
Affinity DataIC50: 598nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365157(CHEMBL1950009)
Affinity DataIC50: 849nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365161(CHEMBL1950013)
Affinity DataIC50: 882nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365162(CHEMBL1950014)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365160(CHEMBL1950012)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365161(CHEMBL1950013)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365162(CHEMBL1950014)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365158(CHEMBL1950010)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365166(CHEMBL1950018)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365166(CHEMBL1950018)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365163(CHEMBL1950015)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365164(CHEMBL1950016)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365158(CHEMBL1950010)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365163(CHEMBL1950015)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365169(CHEMBL1950021)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365168(CHEMBL1950020)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365167(CHEMBL1950019)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365159(CHEMBL1950011)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365165(CHEMBL1950017)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365157(CHEMBL1950009)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365161(CHEMBL1950013)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365163(CHEMBL1950015)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365162(CHEMBL1950014)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365158(CHEMBL1950010)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365166(CHEMBL1950018)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed