Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50034601
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365058(CHEMBL1951067)
Affinity DataKd:  0.708nMAssay Description:Competitive antagonist activity at beta2-adrenoceptor in guinea pig tracheal ring in the presence of N-(5-((1R)-2-(4-(4-(3,4-dimethoxyphenol)-1-oxo-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365060(CHEMBL1951069)
Affinity DataEC50:  19.9nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365059(CHEMBL1951068)
Affinity DataEC50:  126nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365058(CHEMBL1951067)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365057(CHEMBL1951066)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365056(CHEMBL1951065)
Affinity DataEC50:  19.9nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50151720(CHEMBL605993 | Symbicort | cid_9912089 | N-(2-hydr...)
Affinity DataEC50:  0.126nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Guinea pig)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365061(CHEMBL1951070)
Affinity DataEC50:  50.1nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365061(CHEMBL1951070)
Affinity DataIC50: 251nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365060(CHEMBL1951069)
Affinity DataIC50: 257nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365058(CHEMBL1951067)
Affinity DataIC50: 265nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365057(CHEMBL1951066)
Affinity DataIC50: 278nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365056(CHEMBL1951065)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365059(CHEMBL1951068)
Affinity DataIC50: 284nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50042058((4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrroli...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50106185(2H-Phthalazin-1-one | CHEMBL124706)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50365055(CHEMBL82318)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed