Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50040476
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1 using [1-14C]decanoyl-CoA substrate by phospholipid flash plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394735(CHEMBL2165810)
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: 78nMAssay Description:Inhibition of human DGAT1 expressed in human HeLa cells assessed as reduction in triglyceride synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394729(CHEMBL2165816)
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394730(CHEMBL2165815)
Affinity DataIC50: 250nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394736(CHEMBL2165809)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394733(CHEMBL2165812)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DGAT2 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid flash plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394727(CHEMBL2165818)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394728(CHEMBL2165817)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394731(CHEMBL2165814)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394732(CHEMBL2165813)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394734(CHEMBL2165811)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant DGAT1 expressed in insect cell membrane using [1-14C]decanoyl-CoA substrate by phospholipid fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50394726(CHEMBL2165819)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human ERG by manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed